Educators:
Tal Dagan (Associated partner - CAU)
Date:
16.5.18, 08:30-17:00
Location:
Kiel, Am Botanischen Garten 1-9, Room E61
Contents/Learning goals:
The evolutionary history of genes or species is best studied and described by phylogenetic trees. The accumulating sequence data enable the reconstruction of phylogenetic trees for many diverse gene and species. A robust phylogeny is helpful in identifying phyletic groups as well as ancestral relations in the data and lateral gene transfer. Notwithstanding phylogenetic reconstruction is sensitive to various biases in the analysis that originate in alignment and phylogenetic reconstruction artifacts. Students in the workshop will learn to reconstruct multiple sequence alignment and phylogenetic trees of focal sequences. This includes a quantification of possible biases in the phylogenetic reconstruction and ways to counteract their influence on the results. In addition, the students will learn how to identify the root of phylogenetic trees and extract ancestral-descendent relations.
Prerequisites:
None
Tools:
MAFFT, Guidance, PhyML, IQTree, MAD rooting, FigTree.
Keywords:
Tree phylogeny, gene homology, rooting, robustness
Contact:
Tal Dagan,
Registration deadline:
22.4.2018
Registration form:
https://goo.gl/forms/RTWVzzLYKbMtOVOz1
Number of participants is limited to 20. If we receive more applications, we will choose participants based on the relevance of their application and/or a first-come-first-serve basis.