• Saarbrücken

Educators: 
Enrico Seiler (CIBI), Jonas Schulte-Mattler, Svenja Mehringer

Date: 
2026-09-22

Location: 
40th German Conference on Bioinformatics, Saarbrücken, Germany
(#GCB2026,https://gcb2026.de/gcb2026_workshops.html#WS09)

Contents:
Exploration of scalable tools for sequence analysis, focusing on Approximate Membership Queries (AMQ) for short sequence patterns in large reference datasets. Application of the Hierarchical Interleaved Bloom Filter (HIBF) to a read mapper.

Learning goals:

  • Describe the general concept and key applications of AMQ.
  • Apply AMQ to an example read mapper application.
  • Compare the performance of the application with and without AMQ.
  • Gain hands-on experience with modern C++ API integration. 

Prerequisites:

  • Fundamental knowledge of sequencing experiments and associated data.
  • Intermediate programming skills in a high-level language (e.g., Python, Java, or Rust).
  • Basic C++ knowledge (helpful but not mandatory).
  • A laptop to connect to the provided virtual machine.

Keywords:
Sequence analysis, genomics, metagenomics, read alignment, Approximate Membership Query (AMQ), Hierarchical Interleaved Bloom Filter (HIBF), C++, indexing data structures

Tools:
de.NBI Cloud
SeqAn (C++20/23):

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