BRENDA is the world's largest and most widely used information system on all aspects of enzymes, including function, structure, mutants, properties like stability, purification, involvement in diseases etc. The – all together 150 million data in the database are compiled via manual extraction from the primary literature (4 million from >132 000 papers), data integration from e.g. sequence and structure databases, and calculation (genome annotation, membrane association, statistics). Textual and structural input of queries is posssible as well as browsing in EC-. Taxonomy-, ontology-trees. Data download is possible via SOAP.
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Funding: Development and maintenance partially funded by de.NBI.