Get to know Alfred Pühler:
Author: Prof. Dr. Alfred Pühler initiated de.NBI back in 2012. He also was involved in the founding of the Centre for Biotechnology (CeBiTec) at Bielefeld University, where he is head of the research group “Genome Research of Industrial Microorganisms”. At university level, he was appointed honorary member of the Senate.
What's the most memorable science experiment you've conducted or witnessed?
Without doubt, my experimental approach in 1973/74 contributed to the development of genetic engineering in Germany. My research group—at that time based at the Friedrich-Alexander University of Erlangen-Nuremberg—succeeded in introducing genetically modified plasmids into E. coli and bringing them to expression.
What's the most important lesson you've learned in your scientific career?
My scientific career was driven by the insight that the advancement of molecular biology is not possible without powerful bioinformatics. The use of bioinformatics was first established in omics analyses, which then provided the basis for the fields of systems biology and synthetic biology.