TYGS
TYGS – Type (Strain) Genome Server for Genome-Based Prokaryote Taxonomy
TYGS (Type Strain Genome Server) is a web-based platform for genome-based taxonomy of Bacteria and Archaea. Building on the Genome-to-Genome Distance Calculator (GGDC), TYGS provides automated, high-throughput taxonomic analyses using whole-genome comparisons to identify and classify prokaryotic organisms. The platform integrates genome distance calculations, phylogenetic analyses, and comparisons against type strain genomes to support reliable species identification and taxonomic placement. TYGS is complemented by VICTOR for virus phylogeny and classification and is closely linked to the LPSN nomenclature resource.
Key benefits
Automated genome-based taxonomy for bacteria and archaea
High-throughput comparison against type strain genomes
Accurate species identification using genome-to-genome distance calculations
Phylogenomic tree reconstruction and taxonomic placement
User-friendly web interface requiring no local software installation
Integration with established resources including GGDC, VICTOR, and LPSN
Based on state-of-the-art genome comparison methods replacing conventional DNA–DNA hybridization
Applications
Identification and classification of bacterial and archaeal isolates
Genome-based species delineation
Phylogenomic analysis of prokaryotic genomes
Taxonomic characterization of newly sequenced isolates
Comparative microbial genomics
Support for microbial systematics and taxonomy
Intended use
TYGS is intended for microbiologists, microbial taxonomists, bioinformaticians, and life science researchers working with bacterial and archaeal genome sequences. It is particularly suited for users seeking reliable genome-based species identification, phylogenetic analysis, and taxonomic classification using reference type strain genomes.