METALizer
METALizer is a tool for predicting and evaluating the coordination geometry of metal ions in metalloproteins. It compares potential coordination geometries with the arrangement observed in a protein structure and enables interactive assessment of metal–ligand distances against statistics derived from structures in the Protein Data Bank (PDB).
Key benefits
Predicts plausible coordination geometries for metal ions in proteins
Compares predicted and observed metal-binding arrangements
Evaluates metal–ligand interaction distances using PDB-derived statistics
Provides interactive visualization and comparison of coordination geometries
Supports objective assessment of metal-binding site quality
Web-based analysis without local software installation
Applications
Characterization of metal-binding sites in metalloproteins
Validation of metal coordination geometry in experimental structures
Comparison of observed interaction distances with structural reference data
Identification of unusual or potentially incorrect metal-binding arrangements
Analysis of protein–metal and protein–ligand interfaces
Support for structural biology, enzyme research, and structure-based modelling
Intended use
METALizer is intended for structural biologists, crystallographers, bioinorganic chemists, enzymologists, and computational chemists working with metalloprotein structures. It is particularly suited for users who want to evaluate whether an observed metal coordination geometry and its interaction distances are consistent with known structural patterns in the PDB.
Contact:
Website