Educators:
Dr. Aleksandr Zlobin, Dr. Marija Sorokina, Sevilay Gülesen, Max Beining, Christina Wüst, Mateusz Sklodowski (RBC)
Date:
14-18 October 2025
Location:
National Institute of Chemistry, Hajdrihova ulica 19, 1000 LJ, Ljubljana, Slovenia
Contents:
Theoretical introduction into modern approaches of computational protein and drug design, followed by practical hands-on sessions. Technologies covered include
- Rosetta and pyRosetta
- AlphaFold
- ProteinMPNN
- RFdiffusion
- BindCraft
We will discuss their value in designing
- Therapeutic peptides
- Vaccines
- Enzymes
- And other therapeutic modalities
The workshop is open for students and researchers at any career level and is free of charge. The working language of the event is English.
Learning goals:
Understand the space of available protein and drug design technologies, their application scenarios, requirements and limitations. Get experience in applying these tools to model problems. Understand practical considerations of designing proteins and drugs with particular function and therapeutic modality. Learn how to apply computational design tools in your own project.
Prerequisites:
Google account, basic knowledge of Python.
Keywords:
Protein design, enzyme design, drug discovery, structure prediction, AlphaFold, ProteinMPNN, Rfdiffusion, Rosetta
Tools:
Google Colab, ColabFold, AlphaFold, PyMol, Rosetta, pyRosetta, ProteinMPNN, Rfdiffusion, BindCraft
Contact:
Dr. Aleksandr Zlobin,