Martin Golebiewski, Ron Henkel & Andreas Weidemann: HITS, Heidelberg (Germany) (de.NBI-SysBio)
Akira Funahashi & Noriko F Hiroi: Keio University (Yokohama, Japan)
Stefan Hoops: Biocomplexity Institute - Virginia Tech (Blacksburg, VA, USA)
Ursula Kummer, Frank Bergmann, Jürgen Pahle & Sven Sahle: Heidelberg University (Germany) (de.NBI-SysBio/de.NBI-ModSim)
Leslie M. Loew & Michael Blinov: University of Connecticut Health Center (Farmington, CT, USA)
Pedro Mendes: University of Connecticut Health Center (Farmington, CT, USA)
Chris Myers: University of Utah (Salt Lake City, UT, USA)
Saturday, August 12th, 2017 (09:00 – 18:00)
Blacksburg, VA, USA
Participants will learn how to set up computer models of biological systems (e.g. metabolic or
signalling networks) using experimental kinetic data and how to simulate them in different systems
biology platforms. Hands-on sessions, lectures and software demonstrations will be included,
providing attendees with the necessary skills to access experimental kinetics data from available
resources, to assemble computer models with these data, and finally to simulate the generated models
using simulation tools. Also handling and exchange of biological models based on existing community
standards will be demonstrated along with the basic principles of the underlying standard formats.
- Model setup using different software tools and systems biology platforms
- Using experimental data for setting up quantitative models
- Parameter estimation, optimization and model fitting
- Simulation, analysis and visualization of biochemical models
- Database supported modelling: integrated data management and model databases
- Community standards and formats for systems and synthetic biology models
This course aims to introduce services and tools for modelling, simulation and standards in Systems Biology. In addition to presentations the focus will be the Hands-On to allow participants guided a first hand experience.
Having a bit experience with modeling and simulations helps.
Participants are asked to bring their own laptop.
modelling and simulation, parameter estimation, model fitting, database support, comunity standards