Educators:
Daniel Lang (Helmholtz Center, Munich)
Maxim Messerer (Helmholtz Center, Munich)
Date:
11-12.09.2017
Location:
Helmholtz Center Munich
German Research Center for Environmental Health (GmbH)
Ingolstädter Landstr. 1
85764 Neuherberg
Contents:
The workshop explains genefamily concepts and resources. It enables researchers to place their sequence of interest into a genefamily context to compare sequence data and to transfer knowledge from well studied genes.
1. Selecting homologs -how to find members of your gene family
(BLAST und PFAM)
2. Multile alignments - Creation and Modification
3. Phylogenetic tree calculations
4. Interpretation of trees - "What kind of *log is it"? (paralog, ortholog, ...)
Schedule:
Day 1
10:00 Introduction
11:15 Coffee break
11:30 Auswahl vonomologen - Mitglieder der Genfamilie identifizieren
13:00 Lunch
14:00 Multiple alignment - Creation and Modification (part 1)
15:30 Coffee break
15:45 Multiple alignment - Creation and Modification (part 1)
17:00 end day 1
Day 2
10:00 Phylogenetic tree calculation (part 1)
11:15 Coffee break
11:30 Phylogenetic tree calculation (part 2)
13:00 Lunch
14:00 Interpretation of phylogenetic trees (part 1)
15:30 Coffee break
15:45 Interpretation of phylogenetic trees (part 1)
17:00 end day 2
Prerequisites:
1. A gene family or sequence of interest for which the phylogenetic tree will be created
(FASTA/sequence identifier).
2. Laptop
3. skills: Browser, Excel, BLAST
Keywords:
genefamily, multiple alignment, phylogenetic tree, ortholog, paralog
Contact and Registration:
Maxim, Messerer