1OpenMS 00661

LIFS Web Portal: A Comprehensive Suite of Tools for Lipidomics Data Analysis

The LIFS (Lipidomics Informatics for Life Science) web portal offers a comprehensive suite of stand-alone and web-based tools for the analysis of targeted and untargeted mass spectrometry-based lipidomics. The platform provides software for lipid identification, quantification, quality control, visualization, and lipidome comparison, making it an essential resource for researchers in the field.

Key Features:
  • Comprehensive tool suite : The LIFS web portal offers a range of tools that cater to different aspects of lipidomics data analysis, from lipid identification to quantitative lipidome comparison.
  • Stand-alone and web-based applications : Users can choose between stand-alone software and web-based applications, depending on their specific needs and preferences.
  • Information hub for lipidomics : The LIFS web portal serves as a central information hub for lipidomics, hosting resources such as courses, publications, software updates, and conferences.
Tools:
  • LipidXplorer : Software for shotgun lipidomics using an language-driven approach for lipid identification expressed in MFQL (Mass Spectrometry Formula Query Language).
  • Lipidome Projector : Web-based application for quantitative and qualitative lipidome comparison using structure-based lipidome embeddings, developed in cooperation with the University of Hamburg.
  • lxPostman : Web-based application for post-processing of LipidXplorer output files for quality control, quantitation, and merging results.
  • Goslin : Software libraries and web-based application for parsing and normalization of different lipid nomenclatures.
  • LipidCreator : Software for the creation of lipid-specific targeted transition lists for use in mass-spectrometry software like Skyline.
  • LipidCompass : Web-based database and application for the interactive exploration and comparison of quantitative lipidomes.
  • LipidSpace : Software for interactive QC, structure-based quantitative lipidome comparison, statistical analysis, and visualization.
Benefits:
  • Streamlined lipidomics data analysis : The LIFS web portal provides a comprehensive suite of tools that streamline lipidomics data analysis, saving time and effort for researchers.
  • Improved accuracy and reliability : By using standardized tools and methods, researchers can improve the accuracy and reliability of their results.
  • Enhanced collaboration and sharing : The web-based nature of the platform facilitates collaboration and sharing among researchers, promoting a more open and transparent scientific community.
Access:

The LIFS web portal is freely available for academic and non-profit research. Users can access the platform by creating an account on the website.

By providing a comprehensive suite of tools and resources, the LIFS web portal empowers researchers to make new discoveries and advance our understanding of lipid biology.

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