SILVA
SILVA – Comprehensive Resource for Ribosomal RNA Sequence Data
SILVA is a comprehensive, quality-controlled resource for aligned ribosomal RNA (rRNA) gene sequences from the domains Bacteria, Archaea, and Eukaryota. It provides regularly updated reference datasets, taxonomic classifications, and curated guide trees that support a wide range of microbial and phylogenetic analyses. As an ELIXIR Core Data Resource, SILVA is a widely used reference database for microbial community studies and taxonomic assignment workflows.
In addition to its data products, SILVA offers a suite of online tools and services for sequence alignment, taxonomic classification, phylogenetic analysis, primer and probe evaluation, and amplicon sequencing data analysis.
Key benefits
Comprehensive and quality-controlled rRNA reference database
Regularly updated sequence datasets and taxonomic classifications
Curated guide trees reflecting current taxonomy and nomenclature
Supports Bacteria, Archaea, and Eukaryota
ELIXIR Core Data Resource with broad community adoption
Integrated web tools for sequence analysis and phylogenetics
Freely accessible resource for research and education
Applications
Taxonomic classification of ribosomal RNA sequences
Microbiome and microbial community analysis
Amplicon sequencing data processing and interpretation
Phylogenetic tree construction and visualization
Primer and probe evaluation for molecular biology experiments
Reference database for bioinformatics pipelines and workflows
Intended use
SILVA is intended for microbiologists, microbial ecologists, bioinformaticians, evolutionary biologists, and life science researchers working with ribosomal RNA sequence data. It is particularly suited for users requiring high-quality reference sequences and taxonomic information for microbial identification, phylogenetic analyses, and microbiome research.
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