SABIO-RK
SABIO-RK is a manually curated database containing information about biochemical reactions and their kinetic properties. Designed for the needs of systems biology and computational modelling, the database provides kinetic rate equations, parameters, reaction participants and modifiers, together with detailed experimental and environmental conditions.
The structured and standardized data are manually extracted from scientific literature and linked to controlled vocabularies, biological ontologies, and external databases. SABIO-RK supports both interactive access via a web interface and automated integration through web services and APIs. Data can be exported in standardized formats such as SBML and JSON.
Key benefits
Manually curated database of biochemical reactions and kinetic data
Includes experimental conditions and environmental context
Standardized annotations linked to ontologies and external resources
Web interface with full-text and advanced search capabilities
Programmatic access via web services and APIs
Export in standard formats including SBML and JSON
Applications
Construction and parameterization of kinetic models
Systems biology and metabolic pathway modelling
Simulation of biochemical and signalling networks
Integration of kinetic data into computational workflows
Reuse of curated literature-derived reaction parameters
Intended use
SABIO-RK is intended for systems biologists, bioinformaticians, computational modellers, and life science researchers working with biochemical reaction networks and kinetic simulations. It is particularly suited for users who require standardized and curated kinetic data for model development, validation, and integration into simulation workflows.
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