MetaProteomeAnalyzer - identification of taxonomic and functional relationships between identified proteins
The MetaProteomeAnalyzer (MPA) is an intuitive open-source tool for metaproteomics data analysis and interpretation, designed to analyze comprehensive metaproteomics data from tandem mass spectrometry experiments.
Key Features
- Mass Spectra Loading : Loads and stores mass spectra in Mascot Generic Format.
- Protein Database Search : Searches against protein databases (fasta format) using multiple search engines.
- Taxonomic and Functional Analysis : Identifies taxonomic and functional relationships between proteins, providing insights into microbial community composition and function.
- Metaprotein Grouping : Groups proteins into metaproteins to reduce data redundancy and enhance interpretation.
- Metadata Integration : Integrates metadata from UniProt, Kegg Pathways, and NCBI taxonomies to provide a comprehensive understanding of protein functions.
Advanced Features
- Multiple Search Engines : Supports multiple search engines for increased flexibility and accuracy.
- Sample Comparison : Enables comparison of different samples to identify patterns and trends in metaproteomics data.
- Data Exporters : Offers various data exporters for easy analysis and visualization of results.
- BLAST Searches : Allows submission of BLAST searches for further analysis and validation.
Resources
- Intro Videos : Intro videos are available here to provide guidance on using the MetaProteomeAnalyzer software.
Website