SIDER

SIDER is a web-based resource that provides comprehensive information on marketed medicines and their recorded adverse drug reactions. The database contains data extracted from public documents and package inserts, offering a valuable source of knowledge for researchers, clinicians, and patients.

Key Features
  • Adverse Drug Reaction Database: SIDER contains information on 5,868 side effects associated with 1,430 drugs, covering various therapeutic areas.
  • Side Effect Frequency: The database provides frequency data for each side effect, allowing users to assess the likelihood of a particular adverse reaction.
  • Drug and Side Effect Classifications: SIDER offers classifications for both drugs and side effects, facilitating the identification of patterns and relationships between different medications and their potential side effects.
  • Links to Further Information: The database provides links to additional resources, such as drug-target relations, chemical structures, and pharmacokinetic data, enabling users to explore further details about a specific medication or its potential interactions.
Data Coverage

The SIDER database currently covers:

  • 5,868 unique side effects
  • 1,430 marketed drugs
  • Associations between side effects and drugs: over 140,000 annotated associations
Use Cases
  • Pharmacovigilance: Use SIDER to monitor adverse drug reactions and identify potential safety issues with marketed medications.
  • Drug Development: Utilize the database to analyze the side effect profiles of new compounds and compare them with existing medications.
  • Personalized Medicine: Explore the potential interactions between different medications and patient-specific factors, such as age or genetic variations.
Search Functionality

The SIDER website offers a user-friendly search interface that allows users to:

  • Search for specific drugs or side effects
  • Filter results by therapeutic area, drug class, or side effect classification
  • Browse through the database using alphabetical lists of drugs and side effects

By providing access to comprehensive data on marketed medicines and their potential adverse reactions, SIDER aims to support research in pharmacovigilance, personalized medicine, and the development of safer and more effective treatments.

Part of the Human Omics Analysis Toolbox.

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Funding: Neither development nor maintenance funded by de.NBI.