Gear-Genomics
GEAR is a genome analysis web server that provides easy-to-use applications for molecular biologists to analyze DNA sequence data. It supports common laboratory workflows such as Sanger trace analysis, PCR primer design, and general DNA sequence analyses. GEAR combines an intuitive web-based interface with a powerful backend of genomics analysis tools, enabling reliable sequence analysis without requiring extensive bioinformatics expertise. All components of GEAR are fully open-source and freely available, including both the web server front-end and the underlying analysis software.
Key benefits
- Web-based access to genome and sequence analysis tools without local installation
- Designed for routine molecular biology workflows, including Sanger sequencing and PCR primer design
- Fully open-source software stack, ensuring transparency and reproducibility
- Reusable backend command-line tools suitable for standalone or pipeline-based analyses
- Suitable for research, teaching, and method development
Applications
- Analysis and visualization of Sanger sequencing traces
- Quality assessment and inspection of DNA sequences
- Design of PCR primers for experimental workflows
- Sequence analysis using web applications or command-line tools
- Integration of backend tools such as Tracy into custom analysis pipelines
Intended use
GEAR is intended for molecular biologists, geneticists, and life science researchers who work with DNA sequence data and require accessible tools for common sequencing and primer design tasks. It is particularly suited for users who prefer a web-based interface while still benefiting from robust, open-source genomics software.
GEAR is well suited for everyday laboratory workflows, training and teaching environments, and for users who want to reuse or extend the underlying analysis tools in automated or reproducible pipelines.
Funding: Neither development nor maintenance funded by de.NBI

