Stadler Group, Leipzig University, Service Center: RNA Bioinformatics Center - RBC

Many small nucleolar RNAs and many of the hairpin precursors of miRNAs are processed from long non-protein-coding (lncRNA) host genes. In contrast to their highly conserved and heavily structured payload, the host genes feature poorly conserved sequences. Nevertheless, there is mounting evidence that the host genes have biological functions beyond their primary task of carrying a ncRNA as payload.
So far, no connections between the function of the host genes and the function of their payloads have been reported. Here we investigate whether there is evidence for an association of host gene function or mechanisms with the type of payload.

For more information see RNA Bioinformatics Center (RBC) 

Funded by: Federal Ministry of Education and Research (031A538B) and German Academic Exchange Service

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